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Not in CISA KEV
HIGH severity

Vulnerable OpenSSL included in cryptography wheelsGHSA-537c-gmf6-5ccf

HIGH

GHSA-537c-gmf6-5ccf is a high-severity (CVSS 7.5) vulnerability in cryptography. A fix is available for cryptography — see the affected versions and patch details below.

Published
Updated
Affected
1 pkg
Patched
1 / 1
Exploits
None indexed
Exploitation data as of Sep 10, 2026 · OSV.dev, FIRST.org (EPSS)

Real-World Exposure

1 pkg affected
🐍cryptography

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

pyca/cryptography's wheels include a statically linked copy of OpenSSL. The versions of OpenSSL included in wheels prior to cryptograph 48.01 are vulnerable to a security issue. More details about the vulnerability itself can be found in https://openssl-library.org/news/secadv/20260609.txt.

If you are building cryptography source ("sdist") then you are responsible for upgrading your copy of OpenSSL. Only users installing from wheels built by the cryptography project (i.e., those distributed on PyPI) need to update their cryptography versions.

Affected Packages

1 total 1 fixed
EcosystemPackageVulnerable rangeFix
🐍PyPIcryptography≥ 0.5.0&&< 48.0.148.0.1pip install --upgrade 'cryptography==48.0.1'

Detection & mitigation playbook

Open-source dependency

  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for cryptography, including transitive dependencies — a direct dependency you never call can still pull in a vulnerable version.

  2. Fix

    Update cryptography to 48.0.1 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms GHSA-537c-gmf6-5ccf is resolved across your whole dependency graph.

  3. Workarounds

    If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.

Frequently Asked Questions

pyca/cryptography's wheels include a statically linked copy of OpenSSL. The versions of OpenSSL included in wheels prior to cryptograph 48.01 are vulnerable to a security issue. More details about the vulnerability itself can be found in https://openssl-library.org/news/secadv/20260609.txt. If you are building cryptography source ("sdist") then you are responsible for upgrading your copy of OpenSSL. Only users installing from wheels built by the cryptography project (i.e., those distributed on PyPI) need to update their cryptography versions.
O3 Security · Impact-Aware SCA

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Vulnerable OpenSSL included in cryptography wheels