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Not in CISA KEV
HIGH severity

jcvi vulnerable to Configuration Injection due to unsanitized user inputGHSA-x49m-3cw7-gq5q

HIGH

GHSA-x49m-3cw7-gq5q is a high-severity (CVSS 7.1) CWE-77 vulnerability in jcvi. The records list no fixed version yet; check the vendor advisory below and apply the mitigations in the meantime.

Also known asCVE-2023-35932PYSEC-2026-1470
Published
Updated
Affected
1 pkg
Patched
See advisory
Exploits
None indexed
Exploitation data as of Nov 5, 2026 · OSV.dev, NVD, FIRST.org (EPSS)

Exploitation Status

Proof-of-concept exploit code exists

  • CISA’s SSVC triage found public proof-of-concept exploit code for this CVE, though no confirmed active exploitation.
  • A successful exploit gives an attacker total control of the affected component, not partial access.

Exploitation and automatability from CISA’s SSVC triage for GHSA-x49m-3cw7-gq5q.

EPSS Exploitation Probability

via FIRST.org ↗
1.8%probability of exploitation in next 30 days
Lower Risk0.00%
Lower risk than most CVEs78th percentile — riskier than 78% of all scored CVEsHighest risk
0.36%1.02%1.69%2.36%0.9%1.8%May 26Sep 26Nov 26

Probability of exploitation in the next 30 days, from FIRST.org EPSS.

How urgent is this, really

Where this sits among everything scored

Real-World Exposure

1 pkg affected
🐍jcvi

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Summary

A configuration injection happens when user input is considered by the application in an unsanitized format and can reach the configuration file. A malicious user may craft a special payload that may lead to a command injection.

PoC

The vulnerable code snippet is /jcvi/apps/base.py#LL2227C1-L2228C41. Under some circumstances a user input is retrieved and stored within the fullpath variable which reaches the configuration file ~/.jcvirc.

        fullpath = input(msg).strip()
        config.set(PATH, name, fullpath)

I ripped a part of the codebase into a runnable PoC as follows. All the PoC does is call the getpath() function under some circumstances.

from configparser import (
    ConfigParser,
    RawConfigParser,
    NoOptionError,
    NoSectionError,
    ParsingError,
)

import errno
import os
import sys
import os.path as op
import shutil
import signal
import sys
import logging


def is_exe(fpath):
    return op.isfile(fpath) and os.access(fpath, os.X_OK)


def which(program):
    """
    Emulates the unix which command.

    >>> which("cat")
    "/bin/cat"
    >>> which("nosuchprogram")
    """
    fpath, fname = op.split(program)
    if fpath:
        if is_exe(program):
            return program
    else:
        for path in os.environ["PATH"].split(os.pathsep):
            exe_file = op.join(path, program)
            if is_exe(exe_file):
                return exe_file

    return None


def getpath(cmd, name=None, url=None, cfg="~/.jcvirc", warn="exit"):
    """
    Get install locations of common binaries
    First, check ~/.jcvirc file to get the full path
    If not present, ask on the console and store
    """
    p = which(cmd)  # if in PATH, just returns it
    if p:
        return p

    PATH = "Path"
    config = RawConfigParser()
    cfg = op.expanduser(cfg)
    changed = False
    if op.exists(cfg):
        config.read(cfg)

    assert name is not None, "Need a program name"

    try:
        fullpath = config.get(PATH, name)
    except NoSectionError:
        config.add_section(PATH)
        changed = True

    try:
        fullpath = config.get(PATH, name)
    except NoOptionError:
        msg = "=== Configure path for {0} ===\n".format(name, cfg)
        if url:
            msg += "URL: {0}\n".format(url)
        msg += "[Directory that contains `{0}`]: ".format(cmd)
        fullpath = input(msg).strip()
        config.set(PATH, name, fullpath)
        changed = True

    path = op.join(op.expanduser(fullpath), cmd)
    if warn == "exit":
        try:
            assert is_exe(path), "***ERROR: Cannot execute binary `{0}`. ".format(path)
        except AssertionError as e:
            sys.exit("{0!s}Please verify and rerun.".format(e))

    if changed:
        configfile = open(cfg, "w")
        config.write(configfile)
        logging.debug("Configuration written to `{0}`.".format(cfg))

    return path


# Call to getpath
path = getpath("not-part-of-path", name="CLUSTALW2", warn="warn")
print(path)

To run the PoC, you need to remove the config file ~/.jcvirc to emulate the first run,

# Run the PoC with the payload
echo -e "e\rvvvvvvvv = zzzzzzzz\n" | python3 poc.py

image

You can notice the random key/value characters vvvvvvvv = zzzzzzzz were successfully injected.

Impact

The impact of a configuration injection may vary. Under some conditions, it may lead to command injection if there is for instance shell code execution from the configuration file values.

Affected Packages

1 total
EcosystemPackageVulnerable rangeFix
🐍PyPIjcviall versionsNo fix

Affected Products

1 product · 1 configurations
Application
jcvijcvi_project
≤ 1.3.5
range

Detection & mitigation playbook

Open-source dependency
  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for jcvi, including transitive dependencies — a direct dependency you never call can still pull in a vulnerable version.

  2. Remediation status

    The records we use list no patched version of jcvi for GHSA-x49m-3cw7-gq5q. Check the maintainer's advisory, and where your build allows, override or pin the dependency away from the vulnerable range.

  3. Mitigate without a patch

    Stop passing untrusted input into the interpreter or shell: call the affected binary with an argument array rather than a composed command string, reject anything outside a strict allowlist of expected values, and run the component under an account that cannot reach beyond the work it legitimately does.

Frequently Asked Questions

### Summary A configuration injection happens when user input is considered by the application in an unsanitized format and can reach the configuration file. A malicious user may craft a special payload that may lead to a command injection. ### PoC The vulnerable code snippet is [/jcvi/apps/base.py#LL2227C1-L2228C41](https://github.com/tanghaibao/jcvi/blob/cede6c65c8e7603cb266bc3395ac8f915ea9eac7/jcvi/apps/base.py#LL2227C1-L2228C41). Under some circumstances a user input is retrieved and stored within the `fullpath` variable which reaches the configuration file `~/.jcvirc`. ```python
O3 Security · Impact-Aware SCA

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