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Not in CISA KEV
HIGH severity

GHSA-vr3p-gg26-45v9

HIGHFix: openbabel/openbabel@528c142

GHSA-vr3p-gg26-45v9 is a high-severity (CVSS 7.8) Buffer Overflow vulnerability in openbabel. 1 public exploit reference exists, so weaponization risk is real. O3 Security confirms whether GHSA-vr3p-gg26-45v9 is actually reachable in your code before you act, and blocks exploitation at runtime until you patch.

Open Babel has out-of-bounds write in Gaussian coords_type orientation parser

Also known asCVE-2022-37331PYSEC-2026-2793
Published
Jul 1, 2026
Updated
Jul 13, 2026
Affected
1 pkg
Patched
1 / 1
Exploits
1 known
Exploitation data as of Sep 7, 2026 · OSV.dev, NVD, FIRST.org (EPSS)

Exploitation Status

No confirmed exploitation observed yet

  • CISA assesses this as automatable — exploitation doesn’t require manual, per-target effort, which raises the odds of mass scanning and opportunistic attacks.
  • CISA’s own triage has not observed active exploitation or public proof-of-concept code for this CVE as of its last assessment.

Exploitation and automatability from CISA’s SSVC triage for GHSA-vr3p-gg26-45v9.

EPSS Exploitation Probability

via FIRST.org ↗
0.7%probability of exploitation in next 30 days
Lower Risk0.00%
Lower risk than most CVEs50th percentile — riskier than 50% of all scored CVEsHighest risk
0.00%0.39%0.79%1.18%0.1%0.7%Mar 26Jul 26Sep 26

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

How urgent is this, really

GHSA-vr3p-gg26-45v9 plotted by exploitation likelihood (EPSS) against impact (CVSS). The shaded corner — EPSS 50%+ and CVSS 7.0+ — is where this CVE doesn't sit, though severity or exploitability alone can still warrant action.

Where this sits among everything scored

Of 369,023 CVEs with a current EPSS score, this one falls in the < 10% band (highlighted). Real counts from FIRST.org, not a sample — log-scaled since the landscape is heavily right-skewed.

Real-World Exposure

1 pkg affected
🐍openbabel

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Summary

A memory-safety vulnerability in Open Babel's Gaussian output parser allowed an out-of-bounds write when reading a crafted input file.

Details

The flaw was in the coords_type orientation parser inside the Gaussian output reader. A malformed orientation block caused the parser to write past the end of its destination buffer.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious Gaussian output file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/528c142f

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported by Cisco TALOS.

Affected Packages

1 total 1 fixed
EcosystemPackageVulnerable rangeFix
🐍PyPIopenbabelall versions3.2.0
Exploits & PoCs
1

Research use only. For defensive security, authorized penetration testing, and academic research only. Never execute exploit code against systems without explicit written authorization.

Detection & mitigation playbook

Open-source dependency
  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for openbabel. O3's reachability analysis confirms whether the vulnerable code path is actually invoked in your application, so you act on real exposure instead of every transitive match.

  2. Fix

    Update openbabel to 3.2.0 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms GHSA-vr3p-gg26-45v9 is resolved across your whole dependency graph.

  3. Workarounds

    If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.

  4. How O3 protects you

    O3 pinpoints whether GHSA-vr3p-gg26-45v9 is reachable in your code and exactly where to fix it, then blocks exploitation in production at runtime until the patched version is deployed.

Tailored to GHSA-vr3p-gg26-45v9. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

### Summary A memory-safety vulnerability in Open Babel's Gaussian output parser allowed an out-of-bounds write when reading a crafted input file. ### Details The flaw was in the `coords_type` orientation parser inside the Gaussian output reader. A malformed orientation block caused the parser to write past the end of its destination buffer. ### Impact Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a mal
O3 Security · Impact-Aware SCA

Is GHSA-vr3p-gg26-45v9 in your dependencies?

O3 detects GHSA-vr3p-gg26-45v9 across PyPI dependencies and uses function-level reachability to confirm whether the vulnerable code path is actually reachable — not just present. No false positives.

GHSA-vr3p-gg26-45v9: openbabel Memory… | O3 Security