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Not in CISA KEV
HIGH severity

Open Babel has out-of-bounds write in PQS coord_file parserGHSA-f29h-2h58-48r7

HIGHFix: openbabel/openbabel@2a7d2cd

GHSA-f29h-2h58-48r7 is a high-severity (CVSS 7.8) Buffer Overflow vulnerability in openbabel. 1 public exploit reference exists, so weaponization risk is real. A fix is available for openbabel — see the affected versions and patch details below.

Also known asCVE-2022-43467PYSEC-2026-2779
Published
Updated
Affected
1 pkg
Patched
1 / 1
Exploits
1 known
Exploitation data as of Oct 22, 2026 · OSV.dev, NVD, FIRST.org (EPSS)

Exploitation Status

No confirmed exploitation observed yet

  • CISA assesses this as automatable — exploitation doesn’t require manual, per-target effort, which raises the odds of mass scanning and opportunistic attacks.
  • A successful exploit gives an attacker total control of the affected component, not partial access.
  • CISA’s own triage has not observed active exploitation or public proof-of-concept code for this CVE as of its last assessment.

Exploitation and automatability from CISA’s SSVC triage for GHSA-f29h-2h58-48r7.

EPSS Exploitation Probability

via FIRST.org ↗
0.8%probability of exploitation in next 30 days
Lower Risk0.00%
Lower risk than most CVEs57th percentile — riskier than 57% of all scored CVEsHighest risk
0.00%0.45%0.90%1.34%0.4%0.8%Apr 26Aug 26Oct 26

Probability of exploitation in the next 30 days, from FIRST.org EPSS.

How urgent is this, really

GHSA-f29h-2h58-48r7 by exploitation likelihood (EPSS) against impact (CVSS). Outside the shaded patch-first corner.

Where this sits among everything scored

Of 394,803 CVEs with a current EPSS score, this one falls in the < 10% band (highlighted). Counts from FIRST.org, log-scaled.

Real-World Exposure

1 pkg affected
🐍openbabel

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Summary

A memory-safety vulnerability in Open Babel's PQS parser allowed an out-of-bounds write when reading a crafted input file.

Details

The flaw was in the coord_file parsing path of the PQS reader. A malformed coord file specifier caused the parser to write past the end of its destination buffer.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported by Cisco TALOS.

Affected Packages

1 total 1 fixed
EcosystemPackageVulnerable rangeFix
🐍PyPIopenbabelall versions3.2.0pip install --upgrade 'openbabel==3.2.0'

Affected Products

1 product · 1 configurations
Application
open babelopenbabel
1 version
3.1.1
Exploits & PoCs
1

Research use only. For defensive security, authorized penetration testing, and academic research only. Never execute exploit code against systems without explicit written authorization.

Detection & mitigation playbook

Open-source dependency
  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for openbabel, including transitive dependencies — a direct dependency you never call can still pull in a vulnerable version.

  2. Fix

    Update openbabel to 3.2.0 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms GHSA-f29h-2h58-48r7 is resolved across your whole dependency graph.

  3. Workarounds

    Stop feeding it untrusted input: reject or quarantine files and payloads from unverified sources until you can upgrade, restrict accepted formats to the ones you actually need, and run the parsing or decoding step in a least-privileged sandbox or short-lived worker so a crash or corrupted read cannot reach the rest of the process.

Frequently Asked Questions

### Summary A memory-safety vulnerability in Open Babel's PQS parser allowed an out-of-bounds write when reading a crafted input file. ### Details The flaw was in the `coord_file` parsing path of the PQS reader. A malformed coord file specifier caused the parser to write past the end of its destination buffer. ### Impact Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious PQS file with the `obabel
O3 Security · Impact-Aware SCA

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Open Babel has out-of-bounds write in PQS coord_file…