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CVE-2025-10995 — openbabel

Fix: openbabel/openbabel@d4621d4

CVE-2025-10995 is a Buffer Overflow vulnerability in openbabel. A fix is available for openbabel — see the affected versions and patch details below.

Open Babel zipstreamimpl.h underflow memory corruption

Also known asGHSA-8j3x-m868-cpw8PYSEC-2026-2776
Published
Sep 26, 2025
Updated
Aug 12, 2026
Affected
1 pkg
Patched
1 / 1
Exploits
None indexed
Exploitation data as of Sep 28, 2026 · OSV.dev, NVD, FIRST.org (EPSS)

Exploitation Status

Proof-of-concept exploit code exists

  • CISA’s SSVC triage found public proof-of-concept exploit code for this CVE, though no confirmed active exploitation.

Exploitation and automatability from CISA’s SSVC triage for CVE-2025-10995.

EPSS Exploitation Probability

via FIRST.org ↗
0.3%probability of exploitation in next 30 days
Lower Risk0.00%
Lower risk than most CVEs15th percentile — riskier than 15% of all scored CVEsHighest risk

Probability of exploitation in the next 30 days, from FIRST.org EPSS.

Real-World Exposure

1 pkg affected
🐍openbabel

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Summary

A memory-safety vulnerability in Open Babel's bundled zipstream decompression code caused an out-of-bounds write via overlapping memcpy when reading a crafted gzip-compressed chemistry file.

Details

The flaw was in basic_unzip_streambuf::underflow. The decompression buffer refill path invoked memcpy with overlapping source and destination regions, which is undefined behavior and produced out-of-bounds writes in practice. Any file format read through the gzip-wrapped reader was a potential trigger.

Impact

Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious gzip-compressed chemistry file with the obabel tool, the OBConversion API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).

Affected versions

All releases up to and including 3.1.1.

Patched version

3.2.0 (released 2026-05-26).

Patch

Fix commit: https://github.com/openbabel/openbabel/commit/d4621d41 Originally reported as #2832; fixes consolidated in #2913.

A minimized reproducer for this CVE is checked in under test/files/fuzz_regress/ and is exercised on every CI build under ASAN+UBSAN by the fuzzregresstest harness.

Credit

Reported via OSS-Fuzz.

Affected Packages

1 total 1 fixed
EcosystemPackageVulnerable rangeFix
🐍PyPIopenbabelall versions3.2.0pip install --upgrade 'openbabel==3.2.0'

Affected Products

1 product · 1 configurations
Application
open babelopenbabel
≤ 3.1.1
range

Detection & mitigation playbook

Open-source dependency
  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for openbabel, including transitive dependencies — a direct dependency you never call can still pull in a vulnerable version.

  2. Fix

    Update openbabel to 3.2.0 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2025-10995 is resolved across your whole dependency graph.

  3. Workarounds

    Stop feeding it untrusted input: reject or quarantine files and payloads from unverified sources until you can upgrade, restrict accepted formats to the ones you actually need, and run the parsing or decoding step in a least-privileged sandbox or short-lived worker so a crash or corrupted read cannot reach the rest of the process.

Frequently Asked Questions

### Summary A memory-safety vulnerability in Open Babel's bundled zipstream decompression code caused an out-of-bounds write via overlapping `memcpy` when reading a crafted gzip-compressed chemistry file. ### Details The flaw was in `basic_unzip_streambuf::underflow`. The decompression buffer refill path invoked `memcpy` with overlapping source and destination regions, which is undefined behavior and produced out-of-bounds writes in practice. Any file format read through the gzip-wrapped reader was a potential trigger. ### Impact Open Babel is a C++ library and CLI used to read and write
O3 Security · Impact-Aware SCA

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CVE-2025-10995: openbabel | O3 Security