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🐍 PyPI

CVE-2025-10994

Open Babel gamessformat.cpp ReadMolecule use after free

Also known asGHSA-pp85-5j63-xpq3PYSEC-2026-2789
Published
Sep 26, 2025
Updated
Jul 15, 2026
Affected
1 pkg
Patched
1 / 1
Exploits
None indexed

Blast Radius

1 pkg affected
🐍openbabel

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

A weakness has been identified in Open Babel up to 3.1.1. This affects the function GAMESSOutputFormat::ReadMolecule of the file gamessformat.cpp. This manipulation causes use after free. It is possible to launch the attack on the local host. The exploit has been made available to the public and could be exploited.

Affected Packages

1 total 1 fixed
EcosystemPackageVulnerable rangeFix
🐍PyPIopenbabelall versions3.2.0

Detection & mitigation playbook

Open-source dependency
  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for openbabel. O3's reachability analysis confirms whether the vulnerable code path is actually invoked in your application, so you act on real exposure instead of every transitive match.

  2. Fix

    Update openbabel to 3.2.0 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2025-10994 is resolved across your whole dependency graph.

  3. Workarounds

    If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.

  4. How O3 protects you

    O3 pinpoints whether CVE-2025-10994 is reachable in your code and exactly where to fix it, then blocks exploitation in production at runtime until the patched version is deployed.

Tailored to CVE-2025-10994. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

A weakness has been identified in Open Babel up to 3.1.1. This affects the function GAMESSOutputFormat::ReadMolecule of the file gamessformat.cpp. This manipulation causes use after free. It is possible to launch the attack on the local host. The exploit has been made available to the public and could be exploited.
O3 Security · Impact-Aware SCA

Is CVE-2025-10994 in your dependencies?

O3 detects CVE-2025-10994 across PyPI dependencies and uses function-level reachability to confirm whether the vulnerable code path is actually reachable — not just present. No false positives.