How severe is CVE-2022-40897?

CVE-2022-40897 has a CVSS score of 5.9/10, rated MEDIUM. Review your exposure and patch according to your risk tolerance.

Which packages are affected by CVE-2022-40897?

Affected package information for CVE-2022-40897 is not yet fully mapped. Check the official advisory links for details.

How do I fix CVE-2022-40897?

No fixed version has been published for CVE-2022-40897 yet. Monitor the advisory for updates, apply mitigations recommended by the vendor, and use O3 Security to track when a fix becomes available in your stack.

Is CVE-2022-40897 actively exploited in the wild?

Yes. There are 1 known exploit references for CVE-2022-40897, including 1 in-the-wild exploitation observed on GitHub and other sources. Treat this as actively exploitable and prioritize patching immediately. All exploit code should only be run in an isolated sandbox environment for research or authorized testing — never against production systems without explicit written authorization.

What is the EPSS score for CVE-2022-40897?

CVE-2022-40897 has an EPSS (Exploit Prediction Scoring System) score of 0.5%, placing it in the 67th percentile of all CVEs. EPSS is maintained by FIRST.org and estimates the probability that a vulnerability will be exploited in the wild within the next 30 days. This score indicates relatively lower exploitation probability, though the CVSS severity should still guide your patching priority.

CVE-2022-40897

Q: Can O3 Security detect CVE-2022-40897 in my codebase?

Yes. O3 Security's Impact-Aware SCA scanner identifies CVE-2022-40897 across all affected ecosystems (multiple ecosystems), correlates it against your dependency graph, and uses function-level reachability to confirm whether the vulnerable code path is actually reachable in your application — eliminating false positives. You can scan your stack for CVE-2022-40897 directly from the O3 platform.

MEDIUM

Also known asBIT-setuptools-2022-40897GHSA-r9hx-vwmv-q579PYSEC-2022-43012

Published

Dec 23, 2022

Updated

Apr 16, 2026

Affected

0 pkgs

Patched

None yet

Exploits

1 known

EPSS Exploitation Probability

via FIRST.org ↗

0.5%probability of exploitation in next 30 days

Lower Risk67th percentile0.00%

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

Description

Python Packaging Authority (PyPA) setuptools before 65.5.1 allows remote attackers to cause a denial of service via HTML in a crafted package or custom PackageIndex page. There is a Regular Expression Denial of Service (ReDoS) in package_index.py.

Exploits & PoCs

Research use only. For defensive security, authorized penetration testing, and academic research only. Never execute exploit code against systems without explicit written authorization.

Python Packaging Authority (PyPA) setuptools before 65.5.1 allows remote…

pyup.ioNVDDec 2022

Frequently Asked Questions

O3 Security · Impact-Aware SCA

Is CVE-2022-40897 in your stack?

O3 detects CVE-2022-40897 across dependencies and uses function-level reachability to confirm whether the vulnerable code path is actually reachable — not just present. No false positives.

Scan my stack How O3 SCA works

CVSS Score

5.9/10

CVSS v3 base score

Vector breakdown

AV:Attack Vector

Network

AC:Attack Complexity

High

PR:Privileges Required

None

UI:User Interaction