How severe is CVE-2022-21659?

CVE-2022-21659 has a CVSS score of 5.3/10, rated MEDIUM. Review your exposure and patch according to your risk tolerance.

Which packages are affected by CVE-2022-21659?

CVE-2022-21659 affects the following packages: flask-appbuilder (PyPI). Ecosystems affected: PyPI.

How do I fix CVE-2022-21659?

Update flask-appbuilder to 3.4.4 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2022-21659 is resolved across your whole dependency graph.

How do I detect CVE-2022-21659 in my PyPI dependencies?

Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for flask-appbuilder. O3's reachability analysis confirms whether the vulnerable code path is actually invoked in your application, so you act on real exposure instead of every transitive match.

How do I mitigate CVE-2022-21659 if there is no patch (or I can't update yet)?

If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.

How does O3 Security protect against CVE-2022-21659?

O3 pinpoints whether CVE-2022-21659 is reachable in your code and exactly where to fix it, then blocks exploitation in production at runtime until the patched version is deployed.

Is CVE-2022-21659 actively exploited in the wild?

No public exploit code has been indexed for CVE-2022-21659 yet. This does not mean the vulnerability cannot be exploited — absence of public exploits does not imply safety. Apply the recommended fix and use O3 Security to monitor your exposure.

What is the EPSS score for CVE-2022-21659?

CVE-2022-21659 has an EPSS (Exploit Prediction Scoring System) score of 0.9%, placing it in the 56th percentile of all CVEs. EPSS is maintained by FIRST.org and estimates the probability that a vulnerability will be exploited in the wild within the next 30 days. This score indicates relatively lower exploitation probability, though the CVSS severity should still guide your patching priority.

When was CVE-2022-21659 published, and has it been updated?

CVE-2022-21659 was published on January 31, 2022 and was last updated on April 10, 2026. Advisory data evolves as severity scores, affected ranges, and exploit intelligence are revised — always check the latest version of the advisory before acting.

CVE-2022-21659: Observable Response Discrepancy in Flask-AppBui…

EPSS Exploitation Probability

via FIRST.org ↗

0.9%probability of exploitation in next 30 days

Lower Risk56th percentile+0.59%

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

Blast Radius

1 pkg affected

🐍flask-appbuilder

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Flask-AppBuilder is an application development framework, built on top of the Flask web framework. In affected versions there exists a user enumeration vulnerability. This vulnerability allows for a non authenticated user to enumerate existing accounts by timing the response time from the server when you are logging in. Users are advised to upgrade to version 3.4.4 as soon as possible. There are no known workarounds for this issue.

Affected Packages

1 total 1 fixed

Ecosystem	Package	Vulnerable range	Fix
🐍PyPI	`flask-appbuilder`	all versions	3.4.4

Detection & mitigation playbook

Open-source dependency

Detect
Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for flask-appbuilder. O3's reachability analysis confirms whether the vulnerable code path is actually invoked in your application, so you act on real exposure instead of every transitive match.
Fix
Update flask-appbuilder to 3.4.4 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2022-21659 is resolved across your whole dependency graph.
Workarounds
If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.
How O3 protects you
O3 pinpoints whether CVE-2022-21659 is reachable in your code and exactly where to fix it, then blocks exploitation in production at runtime until the patched version is deployed.

Tailored to CVE-2022-21659. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

Flask-AppBuilder is an application development framework, built on top of the Flask web framework. In affected versions there exists a user enumeration vulnerability. This vulnerability allows for a non authenticated user to enumerate existing accounts by timing the response time from the server when you are logging in. Users are advised to upgrade to version 3.4.4 as soon as possible. There are no known workarounds for this issue.

O3 Security · Impact-Aware SCA

Is CVE-2022-21659 in your dependencies?

O3 detects CVE-2022-21659 across PyPI dependencies and uses function-level reachability to confirm whether the vulnerable code path is actually reachable — not just present. No false positives.

Scan my dependencies How O3 SCA works

CVE-2022-21659