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CISA KEV·Added 2022-05-10 — agencies required to remediate by 2022-05-31 · Ransomware

CVE-2022-1388

CRITICAL

On F5 BIG-IP 16.1.x versions prior to 16.1.2.2, 15.1.x versions prior to 15.1.5.1, 14.1.x versions prior to 14.1.4.6, 13.1.x versions prior to 13.1.5, and all 12.1.x and 11.6.x versions,…

Published
May 5, 2022
Updated
Jun 17, 2026
Affected
0 pkgs
Patched
None yet
Exploits
79 known

EPSS Exploitation Probability

via FIRST.org ↗
100.0%probability of exploitation in next 30 days
Very High Risk100th percentile+0.00%
92.8%95.2%97.6%100.0%94.5%100.0%Jan 26May 26Jul 26

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

Description

On F5 BIG-IP 16.1.x versions prior to 16.1.2.2, 15.1.x versions prior to 15.1.5.1, 14.1.x versions prior to 14.1.4.6, 13.1.x versions prior to 13.1.5, and all 12.1.x and 11.6.x versions, undisclosed requests may bypass iControl REST authentication. Note: Software versions which have reached End of Technical Support (EoTS) are not evaluated

Affected Products

11 products · 66 configurations
Application
big-ip access policy managerf5
≥ 16.1.0 && ≤ 12.1.6
range
Application
big-ip advanced firewall managerf5
≥ 16.1.0 && ≤ 12.1.6
range
Application
big-ip analyticsf5
≥ 16.1.0 && ≤ 12.1.6
range
Application
big-ip application acceleration managerf5
≥ 16.1.0 && ≤ 12.1.6
range
Application
big-ip application security managerf5
≥ 16.1.0 && ≤ 12.1.6
range
Application
big-ip domain name systemf5
≥ 16.1.0 && ≤ 12.1.6
range
Exploits & PoCs
79

Research use only. For defensive security, authorized penetration testing, and academic research only. Never execute exploit code against systems without explicit written authorization.

EDB-50932remotemultiple

F5 BIG-IP 16.0.x - Remote Code Execution (RCE)

by Yesith Alvarez · May 12, 2022

Detection & mitigation playbook

Vendor / appliance
  1. Detect

    Inventory every f5 big-ip access policy manager deployment and check each version against the affected-products list above. Because the exploit targets the running system rather than your application code, also watch for exploitation at the network and runtime layer — O3 flags the exploit behaviour from runtime telemetry and egress traffic even before a vulnerable build is confirmed.

  2. Fix

    Apply the f5 big-ip access policy manager security patch or hotfix for CVE-2022-1388 on the affected version, following the vendor advisory for your exact build.

  3. Workarounds

    Cut exposure now: restrict the management/admin interface to trusted networks, segment the device, and apply the vendor's recommended configuration mitigations and any WAF/IPS signature. O3's runtime protection blocks the exploit chain at execution, holding the line on unpatched or end-of-life systems until you can patch.

  4. How O3 protects you

    O3 detects and blocks CVE-2022-1388 exploitation at runtime: eBPF exploit-chain detection, plus L7 egress monitoring that catches the post-exploitation callback and severs the attacker's outbound channel.

Tailored to CVE-2022-1388. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

On F5 BIG-IP 16.1.x versions prior to 16.1.2.2, 15.1.x versions prior to 15.1.5.1, 14.1.x versions prior to 14.1.4.6, 13.1.x versions prior to 13.1.5, and all 12.1.x and 11.6.x versions, undisclosed requests may bypass iControl REST authentication. Note: Software versions which have reached End of Technical Support (EoTS) are not evaluated
O3 Security · Runtime Protection

Is CVE-2022-1388 being exploited in your environment?

O3's eBPF runtime sensors and L7 egress monitoring detect and block the CVE-2022-1388 exploit chain at execution — protecting unpatched and end-of-life systems until the vendor patch is applied.