How severe is CVE-2021-25921?

CVE-2021-25921 has a CVSS score of 5.4/10, rated MEDIUM. Review your exposure and patch according to your risk tolerance.

Which packages are affected by CVE-2021-25921?

Affected package information for CVE-2021-25921 is not yet fully mapped. Check the official advisory links for details.

How do I fix CVE-2021-25921?

No fixed version has been published for CVE-2021-25921 yet. Monitor the advisory for updates, apply mitigations recommended by the vendor, and use O3 Security to track when a fix becomes available in your stack.

Is CVE-2021-25921 actively exploited in the wild?

No public exploit code has been indexed for CVE-2021-25921 yet. This does not mean the vulnerability cannot be exploited — absence of public exploits does not imply safety. Apply the recommended fix and use O3 Security to monitor your exposure.

What is the EPSS score for CVE-2021-25921?

CVE-2021-25921 has an EPSS (Exploit Prediction Scoring System) score of 91.1%, placing it in the 100th percentile of all CVEs. EPSS is maintained by FIRST.org and estimates the probability that a vulnerability will be exploited in the wild within the next 30 days. A score above 50% indicates significantly elevated exploitation risk — immediate patching is strongly recommended.

What type of vulnerability is CVE-2021-25921?

CVE-2021-25921 is classified as Cross-site Scripting (XSS) (CWE-79). This weakness type describe the underlying flaw category, which helps determine the potential impact and the right class of mitigation. This is a high-impact weakness class that often enables remote code execution or data exposure.

When was CVE-2021-25921 published, and has it been updated?

CVE-2021-25921 was published on March 22, 2021 and was last updated on April 10, 2026. Advisory data evolves as severity scores, affected ranges, and exploit intelligence are revised — always check the latest version of the advisory before acting.

CVE-2021-25921: Cross-Site Scripting (Medium 5.4)

EPSS Exploitation Probability

via FIRST.org ↗

91.1%probability of exploitation in next 30 days

Very High Risk100th percentile+60.54%

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

Description

In OpenEMR, versions 2.7.3-rc1 to 6.0.0 are vulnerable to Stored Cross-Site-Scripting (XSS) due to user input not being validated properly in the Allergies section. An attacker could lure an admin to enter a malicious payload and by that initiate the exploit.

Frequently Asked Questions

In OpenEMR, versions 2.7.3-rc1 to 6.0.0 are vulnerable to Stored Cross-Site-Scripting (XSS) due to user input not being validated properly in the `Allergies` section. An attacker could lure an admin to enter a malicious payload and by that initiate the exploit.

O3 Security · Impact-Aware SCA

Is CVE-2021-25921 in your stack?

O3 detects CVE-2021-25921 across dependencies and uses function-level reachability to confirm whether the vulnerable code path is actually reachable — not just present. No false positives.

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