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Not in CISA KEV
MEDIUM severity

CVE-2021-21392

MEDIUMFix: matrix-org/synapse#9240

CVE-2021-21392 is a medium-severity (CVSS 6.3) Open Redirect vulnerability in matrix-synapse. O3 Security confirms whether CVE-2021-21392 is actually reachable in your code before you act, and blocks exploitation at runtime until you patch.

Open redirect via transitional IPv6 addresses on dual-stack networks

Also known asGHSA-5wrh-4jwv-5w78PYSEC-2021-25
Published
Apr 12, 2021
Updated
Jul 8, 2026
Affected
1 pkg
Patched
1 / 1
Exploits
None indexed
Exploitation data as of Jul 8, 2026 · OSV.dev, NVD, FIRST.org (EPSS)

Real-World Exposure

1 pkg affected
🐍matrix-synapse

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Synapse is a Matrix reference homeserver written in python (pypi package matrix-synapse). Matrix is an ecosystem for open federated Instant Messaging and VoIP. In Synapse before version 1.28.0 requests to user provided domains were not restricted to external IP addresses when transitional IPv6 addresses were used. Outbound requests to federation, identity servers, when calculating the key validity for third-party invite events, sending push notifications, and generating URL previews are affected. This could cause Synapse to make requests to internal infrastructure on dual-stack networks. See referenced GitHub security advisory for details and workarounds.

Affected Packages

1 total 1 fixed
EcosystemPackageVulnerable rangeFix
🐍PyPImatrix-synapseall versions1.28.0rc1

Detection & mitigation playbook

Open-source dependency
  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for matrix-synapse. O3's reachability analysis confirms whether the vulnerable code path is actually invoked in your application, so you act on real exposure instead of every transitive match.

  2. Fix

    Update matrix-synapse to 1.28.0rc1 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2021-21392 is resolved across your whole dependency graph.

  3. Workarounds

    If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.

  4. How O3 protects you

    O3 pinpoints whether CVE-2021-21392 is reachable in your code and exactly where to fix it, then blocks exploitation in production at runtime until the patched version is deployed.

Tailored to CVE-2021-21392. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

Synapse is a Matrix reference homeserver written in python (pypi package matrix-synapse). Matrix is an ecosystem for open federated Instant Messaging and VoIP. In Synapse before version 1.28.0 requests to user provided domains were not restricted to external IP addresses when transitional IPv6 addresses were used. Outbound requests to federation, identity servers, when calculating the key validity for third-party invite events, sending push notifications, and generating URL previews are affected. This could cause Synapse to make requests to internal infrastructure on dual-stack networks. See r
O3 Security · Impact-Aware SCA

Is CVE-2021-21392 in your dependencies?

O3 detects CVE-2021-21392 across PyPI dependencies and uses function-level reachability to confirm whether the vulnerable code path is actually reachable — not just present. No false positives.

CVE-2021-21392: matrix-synapse (Medium 6.3) | O3 Security