Your RSA-2048 keys break in 2030. Find every one of them before attackers do.
🛡️
CISA KEV · ACTIVELY EXPLOITED
HIGH severity

CVE-2021-42278

HIGH

CVE-2021-42278 is a high-severity (CVSS 7.5) vulnerability in microsoft windows server 20h2. It is in CISA's Known Exploited Vulnerabilities catalog (added 2022-04-11) and has been used in ransomware campaigns — treat it as actively exploited and patch now. O3 Security detects and blocks CVE-2021-42278 exploitation at runtime via eBPF exploit-chain detection and L7 egress monitoring, even on unpatched systems.

Active Directory Domain Services Elevation of Privilege Vulnerability

Published
Nov 10, 2021
Updated
Aug 19, 2026
Affected
7 products
Patched
See advisory
Exploits
12 known
Exploitation data as of Aug 27, 2026 · OSV.dev, NVD, CISA KEV, FIRST.org (EPSS)

Exploitation Status

Actively exploited in the wild

  • Confirmed by CISA's Known Exploited Vulnerabilities catalog on 2022-04-11 — including use in ransomware campaigns. Federal agencies were required to remediate by 2022-05-02.
  • A successful exploit gives an attacker total control of the affected component, not partial access.

Exploitation and automatability from CISA (KEV catalog and SSVC triage) for CVE-2021-42278.

EPSS Exploitation Probability

via FIRST.org ↗
72.0%probability of exploitation in next 30 days
Very High Risk+1.82%
Lower risk than most CVEs99th percentile — riskier than 99% of all scored CVEsHighest risk
63.0%75.4%87.7%100.0%94.1%72.0%Feb 26Jun 26Aug 26

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

How urgent is this, really

CVE-2021-42278 plotted by exploitation likelihood (EPSS) against impact (CVSS). The shaded corner — EPSS 50%+ and CVSS 7.0+ — is where this CVE sits: patch-first territory.

Where this sits among everything scored

Of 0 CVEs with a current EPSS score, this one falls in the 50–90% band (highlighted). Real counts from FIRST.org, not a sample — log-scaled since the landscape is heavily right-skewed.

Description

Active Directory Domain Services Elevation of Privilege Vulnerability

Affected Products

7 products · 9 configurations
OS
windows server 20h2microsoft
< 10.0.19042.1348
range
OS
windows server 2004microsoft
< 10.0.19041.1348
range
OS
windows server 2008microsoft
1 version
r2
OS
windows server 2012microsoft
1 version
r2
OS
windows server 2016microsoft
< 10.0.14393.4770
range
OS
windows server 2019microsoft
< 10.0.17763.2300
range
Exploits & PoCs
12

Research use only. For defensive security, authorized penetration testing, and academic research only. Never execute exploit code against systems without explicit written authorization.

Detection & mitigation playbook

Vendor / appliance
  1. Detect

    Inventory every microsoft windows server 20h2 deployment and check each version against the affected-products list above. Because the exploit targets the running system rather than your application code, also watch for exploitation at the network and runtime layer — O3 flags the exploit behaviour from runtime telemetry and egress traffic even before a vulnerable build is confirmed.

  2. Fix

    Apply the microsoft windows server 20h2 security patch or hotfix for CVE-2021-42278 on the affected version, following the vendor advisory for your exact build.

  3. Workarounds

    Cut exposure now: restrict the management/admin interface to trusted networks, segment the device, and apply the vendor's recommended configuration mitigations and any WAF/IPS signature. O3's runtime protection blocks the exploit chain at execution, holding the line on unpatched or end-of-life systems until you can patch.

  4. How O3 protects you

    O3 detects and blocks CVE-2021-42278 exploitation at runtime: eBPF exploit-chain detection, plus L7 egress monitoring that catches the post-exploitation callback and severs the attacker's outbound channel.

Tailored to CVE-2021-42278. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

Active Directory Domain Services Elevation of Privilege Vulnerability
O3 Security · Runtime Protection

Is CVE-2021-42278 being exploited in your environment?

O3's eBPF runtime sensors and L7 egress monitoring detect and block the CVE-2021-42278 exploit chain at execution — protecting unpatched and end-of-life systems until the vendor patch is applied.

CVE-2021-42278: Windows Server 20h2… | O3 Security