Your RSA-2048 keys break in 2030. Find every one of them before attackers do.
🐍 PyPI

CVE-2021-21401

HIGH

nanopb vulnerable to invalid free() call with oneofs and PB_ENABLE_MALLOC

Also known asGHSA-7mv5-5mxh-qg88PYSEC-2021-432
Published
Mar 23, 2021
Updated
Apr 11, 2026
Affected
2 pkgs
Patched
2 / 2
Exploits
2 known

EPSS Exploitation Probability

via FIRST.org ↗
1.8%probability of exploitation in next 30 days
Lower Risk76th percentile+0.97%
0.00%0.77%1.54%2.31%0.2%1.8%Dec 25Apr 26Jun 26

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

Blast Radius

2 pkgs affected
🐍nanopb🐍nanopb

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Nanopb is a small code-size Protocol Buffers implementation in ansi C. In Nanopb before versions 0.3.9.8 and 0.4.5, decoding a specifically formed message can cause invalid free() or realloc() calls if the message type contains an oneof field, and the oneof directly contains both a pointer field and a non-pointer field. If the message data first contains the non-pointer field and then the pointer field, the data of the non-pointer field is incorrectly treated as if it was a pointer value. Such message data rarely occurs in normal messages, but it is a concern when untrusted data is parsed. This has been fixed in versions 0.3.9.8 and 0.4.5. See referenced GitHub Security Advisory for more information including workarounds.

Affected Packages

2 total 2 fixed
EcosystemPackageVulnerable rangeFix
🐍PyPInanopb0.3.2&&< 0.3.9.80.3.9.8
🐍PyPInanopb0.4.0&&< 0.4.50.4.5
Exploits & PoCs
2

Research use only. For defensive security, authorized penetration testing, and academic research only. Never execute exploit code against systems without explicit written authorization.

Detection & mitigation playbook

Open-source dependency
  1. Detect

    Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for nanopb. O3's reachability analysis confirms whether the vulnerable code path is actually invoked in your application, so you act on real exposure instead of every transitive match.

  2. Fix

    Update nanopb to 0.3.9.8 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2021-21401 is resolved across your whole dependency graph.

  3. Workarounds

    If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.

  4. How O3 protects you

    O3 pinpoints whether CVE-2021-21401 is reachable in your code and exactly where to fix it, then blocks exploitation in production at runtime until the patched version is deployed.

Tailored to CVE-2021-21401. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

Nanopb is a small code-size Protocol Buffers implementation in ansi C. In Nanopb before versions 0.3.9.8 and 0.4.5, decoding a specifically formed message can cause invalid `free()` or `realloc()` calls if the message type contains an `oneof` field, and the `oneof` directly contains both a pointer field and a non-pointer field. If the message data first contains the non-pointer field and then the pointer field, the data of the non-pointer field is incorrectly treated as if it was a pointer value. Such message data rarely occurs in normal messages, but it is a concern when untrusted data is par
O3 Security · Impact-Aware SCA

Is CVE-2021-21401 in your dependencies?

O3 detects CVE-2021-21401 across PyPI dependencies and uses function-level reachability to confirm whether the vulnerable code path is actually reachable — not just present. No false positives.