How severe is CVE-2025-66221?

No CVSS score has been assigned to CVE-2025-66221 yet. Review the advisory details and affected package list to assess your exposure.

Which packages are affected by CVE-2025-66221?

CVE-2025-66221 affects the following packages: werkzeug (PyPI). Ecosystems affected: PyPI.

How do I fix CVE-2025-66221?

Update werkzeug to 3.1.4 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2025-66221 is resolved across your whole dependency graph.

How do I detect CVE-2025-66221 in my PyPI dependencies?

Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for werkzeug, including transitive dependencies — a direct dependency you never call can still pull in a vulnerable version.

How do I mitigate CVE-2025-66221 if there is no patch (or I can't update yet)?

If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.

How does O3 Security protect against CVE-2025-66221?

O3 Security's impact-aware SCA analyses which vulnerable code paths your application actually calls, so a match like CVE-2025-66221 can be triaged on real exposure rather than presence alone.

Is CVE-2025-66221 actively exploited in the wild?

No public exploit code has been indexed for CVE-2025-66221 yet. This does not mean the vulnerability cannot be exploited — absence of public exploits does not imply safety. Apply the recommended fix and use O3 Security to monitor your exposure.

What is the EPSS score for CVE-2025-66221?

CVE-2025-66221 has an EPSS (Exploit Prediction Scoring System) score of 0.5%, placing it in the 41th percentile of all CVEs. EPSS is maintained by FIRST.org and estimates the probability that a vulnerability will be exploited in the wild within the next 30 days. This score indicates relatively lower exploitation probability, though the CVSS severity should still guide your patching priority.

What type of vulnerability is CVE-2025-66221?

CVE-2025-66221 is classified as CWE-67 (CWE-67). This weakness type describe the underlying flaw category, which helps determine the potential impact and the right class of mitigation.

When was CVE-2025-66221 published, and has it been updated?

CVE-2025-66221 was published on November 29, 2025 and was last updated on August 12, 2026. Advisory data evolves as severity scores, affected ranges, and exploit intelligence are revised — always check the latest version of the advisory before acting.

CVE-2025-66221: werkzeug

Exploitation Status

No confirmed exploitation observed yet

CISA assesses this as automatable — exploitation doesn’t require manual, per-target effort, which raises the odds of mass scanning and opportunistic attacks.
CISA’s own triage has not observed active exploitation or public proof-of-concept code for this CVE as of its last assessment.

Exploitation and automatability from CISA’s SSVC triage for CVE-2025-66221.

EPSS Exploitation Probability

via FIRST.org ↗

0.5%probability of exploitation in next 30 days

Lower Risk0.00%

Lower risk than most CVEs41th percentile — riskier than 41% of all scored CVEsHighest risk

EPSS (Exploit Prediction Scoring System) is a daily probability model maintained by FIRST.org. It estimates the likelihood a CVE will be exploited in production environments within the next 30 days, derived from real-world threat intelligence signals.

Real-World Exposure

1 pkg affected

🐍werkzeug

Real-time download stats are indexed for npm and PyPI packages. This vulnerability affects PyPI packages — download data is not available via public APIs for these ecosystems.

Description

Werkzeug is a comprehensive WSGI web application library. Prior to version 3.1.4, Werkzeug's safe_join function allows path segments with Windows device names. On Windows, there are special device names such as CON, AUX, etc that are implicitly present and readable in every directory. send_from_directory uses safe_join to safely serve files at user-specified paths under a directory. If the application is running on Windows, and the requested path ends with a special device name, the file will be opened successfully, but reading will hang indefinitely. This issue has been patched in version 3.1.4.

Affected Packages

1 total 1 fixed

Ecosystem	Package	Vulnerable range	Fix
🐍PyPI	`werkzeug`	all versions	3.1.4`pip install --upgrade 'werkzeug==3.1.4'`

Detection & mitigation playbook

Open-source dependency

Detect
Scan your dependency tree (package-lock.json, pnpm-lock.yaml, requirements.txt, go.sum, etc.) for werkzeug, including transitive dependencies — a direct dependency you never call can still pull in a vulnerable version.
Fix
Update werkzeug to 3.1.4 or later, then make sure no transitive (indirect) dependency still pins the vulnerable range — O3 confirms CVE-2025-66221 is resolved across your whole dependency graph.
Workarounds
If you can't upgrade right away: gate or disable the affected feature, validate untrusted input at the boundary, and avoid passing attacker-controlled data into the vulnerable path. O3's runtime protection blocks exploitation in production as an interim safeguard until the upgrade lands.
How O3 protects you
O3 Security's impact-aware SCA analyses which vulnerable code paths your application actually calls, so a match like CVE-2025-66221 can be triaged on real exposure rather than presence alone.

Tailored to CVE-2025-66221. Runtime protection reduces exposure until a permanent patch is applied and verified — it complements patching, it doesn't replace it.

Frequently Asked Questions

Werkzeug is a comprehensive WSGI web application library. Prior to version 3.1.4, Werkzeug's safe_join function allows path segments with Windows device names. On Windows, there are special device names such as CON, AUX, etc that are implicitly present and readable in every directory. send_from_directory uses safe_join to safely serve files at user-specified paths under a directory. If the application is running on Windows, and the requested path ends with a special device name, the file will be opened successfully, but reading will hang indefinitely. This issue has been patched in version 3.1

O3 Security · Impact-Aware SCA

Is CVE-2025-66221 in your dependencies?

O3 Security finds CVE-2025-66221 across PyPI dependencies, including transitive ones, and its impact-aware SCA ranks findings by whether your code actually calls the vulnerable path.

Scan my dependencies How O3 SCA works

CVE-2025-66221 — werkzeug