{"id":"CVE-2022-46280","aliases":["GHSA-8qxc-57hf-hc9j","PYSEC-2026-2777"],"url":"https://o3.security/vulnerability/CVE-2022-46280","summary":"Open Babel has uninitialized pointer dereference in PQS pFormat","details":"### Summary\n\nA memory-safety vulnerability in Open Babel's PQS parser caused an\nuninitialized pointer dereference when reading a crafted input file.\n\n### Details\n\nThe flaw was in the `pFormat` handling of the PQS reader. A malformed\ninput caused the parser to dereference a format pointer that had\nnever been initialized.\n\n### Impact\n\nOpen Babel is a C++ library and CLI used to read and write chemistry\nfile formats; it is shipped by Linux distributions and embedded in\nservices that may parse untrusted input. Triggering this vulnerability\nrequires the victim to open a malicious PQS file with the `obabel`\ntool, the `OBConversion` API, or any of the language bindings (Python,\nRuby, Java, R, Perl, C#, PHP).\n\n### Affected versions\n\nAll releases up to and including 3.1.1.\n\n### Patched version\n\n3.2.0 (released 2026-05-26).\n\n### Patch\n\nFix commit: https://github.com/openbabel/openbabel/commit/2a7d2cda\n\nA minimized reproducer for this CVE is checked in under\n`test/files/fuzz_regress/` and is exercised on every CI build under\nASAN+UBSAN by the `fuzzregresstest` harness.\n\n### Credit\n\nReported by Cisco TALOS.","published":"2023-07-21T21:15:10.660Z","modified":"2026-07-13T16:43:26.104564797Z","cvss":{"score":7.8,"severity":"HIGH","vector":"CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H"},"epss":{"score":0.00828,"percentile":0.55697,"asOf":"2026-09-16"},"cisaKev":null,"exploitsKnown":1,"affectedPackages":[{"ecosystem":"PyPI","name":"openbabel","fixedVersion":"3.2.0"}],"fix":{"url":"https://github.com/openbabel/openbabel/commit/2a7d2cda8bd47daade2e555e34b69651a2e132ef","label":"openbabel/openbabel@2a7d2cd"},"references":[{"type":"WEB","url":"https://www.talosintelligence.com/vulnerability_reports/TALOS-2022-1670"},{"type":"EVIDENCE","url":"https://talosintelligence.com/vulnerability_reports/TALOS-2022-1670"},{"type":"WEB","url":"https://github.com/openbabel/openbabel/security/advisories/GHSA-8qxc-57hf-hc9j"},{"type":"ADVISORY","url":"https://nvd.nist.gov/vuln/detail/CVE-2022-46280"},{"type":"WEB","url":"https://github.com/openbabel/openbabel/commit/2a7d2cda8bd47daade2e555e34b69651a2e132ef"},{"type":"PACKAGE","url":"https://github.com/openbabel/openbabel"}],"provenance":{"sources":["OSV.dev","FIRST.org (EPSS)"],"lastVerified":"2026-07-13T16:43:26.104564797Z"}}